This guide is concerning the promotion of management, improvement and understanding of the amount of specific chemical substances released into the environment. Part A provides an overview of chemical risk assessment and provides an overview of chemical management. It is a content that deepens understanding. Part B explains the Pollutant Release and Transfer Register (PRTR) Law and the SDS system based on the PRTR Law and GHS classification using the GHS Classification Guidance is explained. Also of the mixture It also introduces the "GHS Classification System for Mixtures", a tool to support the implementation of GHS classification.